Health and Medical Treatment

Posts Tagged ‘Tumor’

Elements of the environment, such as ultraviolet radiation or electromagnetic fields, food preservatives or antibiotics, can cause temporary immunosuppression. Stress or the practice of intensive physical exercise also have harmful effects on the immune system. Numerous data indicate that after intensive training, athletes generally healthy frequently suffer from colds or other respiratory infections because their immune system was weakened by the exercise.

Similar immunosuppression was observed in patients subjected to physical or emotional stress, and in patients suffering from stress related illnesses. Under such conditions, the number of macrophages available is reduced, they become unable to participate in the immune cascade, further exacerbating the immunosuppression. It was demonstrated that beta-(1,3 / 1,6)-glucan stimulates and activates macrophages to counteract these immunosuppressive effects. Research has shown that beta glucan enhances the phagocytosis of micro-organisms responsible for the development of infections. In addition, beta-(1,3 / 1,6)-glucan increases the ability of macrophages to destroy tumor cells. It activates macrophages and, through them, the entire immune cascade including T and B cells

The experiments on humans with glucans begins in the 1970s after extensive animal studies. In 1975, the beneficial effects of beta-glucan in cancer treatment were highlighted by Peter W. Mansell. The researchers injected the cancer supplements beta 1 3d glucan in the subcutaneous nodules of malignant cancer of the skin of nine patients. In five days, the size of cancerous lesions was significantly reduced and those of smaller size were completely healed. When biopsies were done at the site of injection, no evidence of melanoma was found but, against a collection of obviously activated macrophages. Then, researchers from the School of Medicine at Tulane University treated a number of women with recurrent malignant ulcers of the chest wall following mastectomy and radiation therapy for breast cancer . They injected the beta-1 ,3-glucan directly into malignant ulcers: the wounds were completely healed. Then, the same treatment was used on large pressure ulcers at the Charity Hospital in New Orleans, with a total success. An unexpected benefit was the complete absence of infection and the rapidity with which the skin has resumed a normal appearance.

Beta-glucan is a complex carbohydrate found in cell walls of yeast, oats, barley, and mushrooms. These complex carbohydrates is also called a polysaccharide, which means a sugar molecule complex derived from many channels. The most common is the purest form of beta-glucan, which is extracted from yeast cell walls. It is common to find this excerpt dense molecular referred to its scientific name, Saccharomyces cerevasiae. The most common use for beta-glucan in modern science of nutrition is the intake with the intention of strengthening the immune system response.

To date, the beta-glucan has been clinically proven to help lower cholesterol. There is convincing evidence that beta-glucan using the immune system to delay the growth of cancer, fight infection, improve the intestinal flora, and in topical applications, reduce wrinkles. Research is still ongoing on what appears to be a promising nutritional supplement to improve immune system function of cellular activity.

We’ve been known that the yeast and other sources of beta-glucans and a number of beneficial physiological effects on the cardiovascular system, both in relation to natural immunity. The role they play in preventing and fighting infections has been proven too, that the ability of CR3 (complement receptor 3) receptor activation enables these cells to destroy tumor cells identified by fragments of complement C3. Beta glucan are glucose polymers that are synthesized by plants and microorganisms in a wide spectrum of oats, barley, mushrooms, marine algae and certain bacteria from the yeast cells. A traditional medicine for centuries, but a description of molecular structures, determination until the 20th mid-century in coming.

The beta-glucan in vivo the same mechanism helps neutrophils recognize and destroy tumor cells, such as that of the first reaction against pathogenic agents in connection with earlier. So much difference that the antibodies are not cell-surface antigens of pathogens, but the tumor cell surface antigens exist, which followed a 3-complement proteins bind to the cell surface. The beta-glucan by activation of complement receptor 3 (CR3) in neutrophils is thus able to recognize and destroy abnormal cells.

Although the body normally produces antibodies in cancer patients against the cancer, these antibodies are often not in itself sufficient to induce complement-3 protein linked to the tumor cell surface. In some patients. 20% to produce enough antibodies to beta glucan for cancer, monoclonal antibodies are injected from the outside without any significant improvement or complete remission can be achieved.

The natural immune beta-glucans to “turn on” the fight against cancers of the immune tumort for  opened a new chapter in which the “immuno-chemotherapy,” the name given to researchers. In preclinical tests, after a few dozen, delivered an incurable patient also used the “immuno-chemotherapy”, many of whom were complete remission. Do you have a patient who had tumor-free for over 6 years, previously diagnosed with peritoneal gyomorcarcinoma  not detectable in the body . The beta-glucans ten times the therapeutic dose is administered after a lot of side effects were observed, which makes it very secure implementation.

Treatment of patients has several aspects:

1. It is primarily surgical removal of the tumor, an operation usually possible if it is located, or if the spin did not exceed the neighboring nodes.

2. Radiotherapy, less mutilating, it is sometimes preferred, and often it is associated. It can be external (y radiocobalt rays or X-ray Betatron) or internal (hollow needle containing a radioactive metal ingested radioiodine in thyroid cancer cases).

3. Hormone therapy is appropriate in cases of cancer spread, because the cells, even malignant, remain hormone-dependent. It is used mainly in cases of sexual organs: prostate, breast.

4. Chemotherapy (thirty synthetic products, plant alkaloids, antibiotics), by slowing mitosis, produces remissions, particularly in the case of leukemia.

5. Immunotherapy, finally, strengthens the immune reactions in the body. It acts, either non-specific (by inoculation of BCG, for example), or specifically, when using antigens produced by the tumor. This method is effective only if the number of malignant cells is low, so use it rarely does one only: if the main focus was removed by surgical approach, radiotherapy and chemotherapy destroy the essential disseminated malignant cells, and immunotherapy removes what remains.